Skip to main content

Table 1 Next-generation sequencing of the diagnostic bone marrow aspirate and left gingival lesion

From: Myeloid transformation of plasma cell myeloma: molecular evidence of clonal evolution revealed by next generation sequencing

Bone marrow aspirate

Soft tissue

BRAF1 G466A subclonal, G469 subclonal

BRAF G469A

KRAS A146V

KRAS A146V

IGH IGH-MAF rearrangement

IGH IGH-MAF rearrangement

CDKN2A/B loss

CDKN2A/B loss

MAP3K6 Q943, truncation exon 22

MAP3K6 Q943, truncation exon 22

TRAF3 R505

NF1 R2450

PTPRO E379K – subclonal

CCT6B splice site 615-2A > G TNFAIP3 W85