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Table 2 Histological, immunohistochemical and molecular findings in reported colorectal perineuriomas (Total: 158)

From: Colonic perineurioma (benign fibroblastic polyp): case report and review of the literature

Ref.

No of cases

Serrated crypts

EMA+a

Claudin-1+

GLUT1+

Collagen IV+

CD34+a

BRAF mutation

[1]

14

3/14

0/14

ND

ND

ND

3/14

ND

[10, 11]

5

2/4

3/5

4/5

5/5

ND

2/4

ND

[8]

9

5/9

9/9

4/9

ND

ND

2/9

ND

[7]

4

4/4

ND

ND

ND

ND

0/4

ND

[2, 5, 12, 15]

60

45/60

39/45

40/45

42/45

45/45

0/10

5/20

[9]

4

NS

4/4

4/4

4/4

ND

ND

ND

[13]

1

1/1

NS

NS

NS

1/1

ND

ND

[14]

1

0/1

ND

ND

ND

ND

0/1

ND

[3]

29

29/29

21/26

15/17

20/26

17/17

8/27

14/22

[4]

20

18/20

20/20

ND

ND

ND

ND

18/20

[16]

9

NS

7/9

9/9

7/9

ND

ND

ND

[17]

1

NS

0/1

ND

1/1

1/1

1/1

ND

Current case

1

1/1

1/1

ND

1/1

1/1

0/1

1/1 (IHC)

Total

158

108/143

75%

104/134

78%

76/89

85%

80/91

88%

65/65

100%

16/71

23%

38/63

60%

  1. aEMA and CD34 staining often described as weak and/or focal
  2. ND Not done, NS Not specified, IHC Immunohistochemistry