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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Does heterogeneity matter in the estimation of tumour budding and tumour stroma ratio in colon cancer?

Fig. 2

Counting tumour budding in a high power field (HPF). The number of tumour buds (TB) was counted along the invasive front on cytokeratin AE1/AE3 stained sections in 10 HPF. A tumour bud was defined as an isolated single tumour cell or a cluster of up to four tumour cells (arrows). Adenocarcinoma cells without a clear nucleus and cytoplasmatic fragments (arrowheads) were not counted. Magnification 40×

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