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Table 5 Intra- and inter-observer agreement data for scoring of tumour budding

From: Does heterogeneity matter in the estimation of tumour budding and tumour stroma ratio in colon cancer?

 

N

Kappa values (Cut-off ≥10 buds)

Weighted kappa values (Continuous TB-scale)

TB-A1 & TB-A2

129

0.60, p < 0.001

0.70, p < 0.001

TB-A1 & TB-A2

43

0.79, p < 0.001

0.79, p < 0.001

TB-A1 & TB-B

50

0.46, p < 0.001

0.54, p < 0.001

TB-A2 & TB-B

50

0.73, p < 0.001

0.59, p < 0.001

  1. Kappa was calculated for continuous data and for data divided into categories as low-budding and high-budding with a cut-off for high-budding of ≥10 buds. Intra-observer kappa was calculated for all sections (n = 129) and for the deepest invasive tumour section (n = 43). Inter-observer kappa was calculated for 50 randomly selected cases
  2. Abbreviations: TB tumour budding; A1 First count by observer A; A2 second count by observer A; B count by observer B
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Diagnostic Pathology

ISSN: 1746-1596

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