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Table 6 Scoring criteria for semi-quantitative estimation of tumour stroma ratio with a list of structures to be included or excluded in the estimation

From: Does heterogeneity matter in the estimation of tumour budding and tumour stroma ratio in colon cancer?

Structure

Inclusion

Handling of problem

Necrosis

No

Select another area or another section if possible

Mucin

No

Select another area

Major vascular structures

No

Visual exclusion

Minor vascular structures

Yes

Smooth muscle tissue

No

Masson’s trichrome or desmin stains

Nerves

Yes

Lymphocytes

Yes

Dense infiltrates with neutrophil granulocytes are excluded as necrosis

Adenoma

No

Visual exclusion