Table 3 Protein expressions related with histologic severity of hepatic steatosis
pSTAT3 in hepatocytes | Estrogen-receptor α in hepatocytes | pSTAT3 in hepatic stellate cells | |||||||
|---|---|---|---|---|---|---|---|---|---|
negative | positive | P value | focal | diffuse | P value | negative | positive | P value | |
Lobular inflammation (inflammatory foci/ 200× field) | 0.028 | 0.022 | 0.016 | ||||||
< 2 | 16 (55%) | 5 (17%) | 3 (10%) | 18 (62%) | 20 (69%) | 1 (3%) | |||
2–4 | 2 (7%) | 4 (14%) | 2 (7%) | 4 (14%) | 3 (10%) | 3 (10%) | |||
> 4 | 0 | 2 (7%) | 2 (7%) | 0 | 1 (3%) | 1 (3%) | |||
Ballooning degeneration | 0.010 | 0.001 | 0.033 | ||||||
none | 10 (34%) | 1 (3%) | 0 | 11 (38%) | 11 (38%) | 0 | |||
few | 7 (24%) | 5 (17%) | 2 (7%) | 10 (34%) | 10 (34%) | 2 (7%) | |||
many | 1 (3%) | 5 (17%) | 5 (17%) | 1 (3%) | 3 (10%) | 3 (10%) | |||
Fibrosis | 0.001 | 0.000 | 0.000 | ||||||
absent | 11 (38%) | 0 | 0 | 11 (38%) | 11 (38%) | 0 | |||
milda | 6 (231%) | 4 (14%) | 0 | 10 (34%) | 10 (34%) | 0 | |||
advancedb | 1 (3%) | 7 (24%) | 7 (24%) | 1 (3%) | 3 (10%) | 5 (17%) | |||