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Table 3 Protein expressions related with histologic severity of hepatic steatosis

From: Expression patterns of STAT3, ERK and estrogen-receptor α are associated with development and histologic severity of hepatic steatosis: a retrospective study

  pSTAT3 in hepatocytes Estrogen-receptor α in hepatocytes pSTAT3 in hepatic stellate cells
negative positive P value focal diffuse P value negative positive P value
Lobular inflammation (inflammatory foci/ 200× field) 0.028    0.022    0.016
 < 2 16 (55%) 5 (17%)   3 (10%) 18 (62%)   20 (69%) 1 (3%)  
 2–4 2 (7%) 4 (14%)   2 (7%) 4 (14%)   3 (10%) 3 (10%)  
 > 4 0 2 (7%)   2 (7%) 0   1 (3%) 1 (3%)  
Ballooning degeneration   0.010    0.001    0.033
 none 10 (34%) 1 (3%)   0 11 (38%)   11 (38%) 0  
 few 7 (24%) 5 (17%)   2 (7%) 10 (34%)   10 (34%) 2 (7%)  
 many 1 (3%) 5 (17%)   5 (17%) 1 (3%)   3 (10%) 3 (10%)  
Fibrosis    0.001    0.000    0.000
 absent 11 (38%) 0   0 11 (38%)   11 (38%) 0  
 milda 6 (231%) 4 (14%)   0 10 (34%)   10 (34%) 0  
 advancedb 1 (3%) 7 (24%)   7 (24%) 1 (3%)   3 (10%) 5 (17%)  
  1. aperisinusoidal, portal &/or periprotal fibrosis
  2. bbridging fibrosis or cirrhosis