Table 1 Summary of OFMT cases in the oral/head and neck region reported from 1989 to 2016
From: Ossifying Fibromyxoid tumor of soft parts in head and neck: case report and literature review
Reference | Patients (n) | Age (y) | Sex | Location | Clinical presentation | Surgical treatment | Mitotic activity | Atypia | Recurrence | Metastasis | Follow-up |
|---|---|---|---|---|---|---|---|---|---|---|---|
Enzinger FM et al. (1989) [1] | 8 | 14–79 (mean 47) | 64% M | Head and neck, various sites | Slow growing painless mass | Local excision (majority of cases) | N/D | N/D | N/D | No | 1–32 y (mean 6.2) |
Schofield JB et al. (1993) [7] | 4 | 41 | M | Inner cheek | Slow growing mass | N/D | – | – | No | No | 1–10 y (median 7) |
| Â | 78 | M | Neck | Slow growing mass | N/D | N/D | N/D | No | No | Â | |
|  | 39 | M | Lip | Slow growing mass | N/D | 0–11/10 HPFs | – | No | No |  | |
| Â | 49 | M | Pretracheal | Slow growing mass | N/D | N/D | N/D | No | No | Â | |
Williams SB et al. (1993) [4] | 9 | 51 | F | Posterior neck | Slow growing mass | Local excision | – | – | No | No | 2 y |
|  | 52 | M | Submental area | Slow growing mass | Local excision | – | – | No | No | N/D | |
|  | 39 | M | Chin | Slow growing mass | Local excision | – | – | No | No | 2 y | |
|  | 67 | F | L mandible vestibule | Slow growing mass | Local excision | – | – | No | No | 1.5 y | |
|  | 29 | M | L lateral max and nasal bone | Slow growing mass | Local excision | – | – | No | No | 1.5 y | |
|  | 37 | M | Soft palate | Slow growing mass | Local excision | – | – | No | No | 3 y | |
|  | 66 | M | Scalp | Slow growing mass | Local excision | – | – | No | No | 2 y | |
|  | 75 | M | L neck | Slow growing mass | Local excision | – | – | No | No | 1 y | |
| Â | 58 | F | L parapharynx | Slow growing mass | Local excision | + | + | Yes (2) | No | 2.1 y | |
Williams RW et al. (1994) [8] | 1 | 35 | M | Parotid/zygomatic arch region | Slow growing mass | Wide local excision | + | + | Yes (3) | No | 24 y |
Ng WK et al. (1995) [9] | 1 | 52 | M | R nostril, middle meatus | Swelling, intermittent epiphora | N/D | N/D | N/D | N/D | N/D | N/D |
Thompson J et al. (1995) [10] | 1 | 35 | M | L nasal cavity | Congestion and pain | Partial removal | – | – | Yes | No | N/D |
Lax S et al. (1995) [11] | 1 | 50 | M | R thyroid lobe | Nodular enlargement | Total thyroidectomy | + | – | No | No | 3 y |
Zamecnik M et al. (1997) [12] | 2 | 71 | M | Neck | Subcutaneous mass | Surgical removal | + | + | Yes (2) | No | 4 y |
| Â | 45 | F | Neck | Subcutaneous mass | Surgical removal | + | + | Yes | Yes (lung) | DOD | |
Ekfors TO et al. (1998) [13] | 2 | 63 | M | Neck | Subcutaneous mass | N/D | + | – | No | No | N/D |
|  | 2 | F | Head | Subcutaneous mass | N/D | – | – | No | No | N/D | |
Paschen C et al. (2001) [14] | 1 | 12 | M | Nasal cavity and paranasal sinus | Nasal congestion | Local excision | – | – | No | No | N/D |
Folpe AL et al. (2003) [15] | 9 | 14–80 (median 49) | 56% M | Head and neck, various sites | Subcutaneous mass | Wide excision (majority of cases) | 1 patient | – | Yes (2 in single patient) | 1 patient (leg) | 5–240 mo (mean 57) |
Al-Mazrou KA (2004) [16] | 1 | 3-wk. infant | M | L nasomaxillary fold | Slight fullness | Local excision | – | – | No | No | 6 mo |
Mollaoglu N et al. (2006) [17] | 1 | 13 | M | L side of mandible | Rapid swelling | Local excision | – | – | No | No | p |
Park DJ et al. (2006) [18] | 1 | 81 | F | R orbit | Diplopia, pain, swelling | Local excision | – | – | Yes (2) | No | 6 y |
Seykora JT et al. (2006) [19] | 1 | 67 | F | Scalp | Multilobular and cystic mass | Wide local excision | 2/10 HPFs | – | No | No | 8 y |
Suehiro K et al. (2006) [20] | 1 | 38 | F | Scalp | Subcutaneous mass | Local excision | 5/10 HPFs | – | Yes (3) | Yes (lung, brain) | DOD |
Blum A et al. (2006) [21] | 1 | 49 | F | Nasal septum | Nasal congestion and swelling | Local excision | – | – | No | No | 1 mo |
Miliaras D et al. (2007) [22] | 1 | 39 | M | Mandibular symphysis skin | Slow growing, subcutaneous mass | Local excision | – | – | No | No | 1 y |
Hirose T et al. (2007) [23] | 2 | 42 | M | Nasal vestibule | N/D | Local excision | + | + | Yes (2) | No | 17 y |
|  | 54 | M | L supraclavicular region | Small nodule | Local excision | – | – | No | No | 6 mo | |
Sharif MA et al. (2008) [24] | 1 | 14 | F | Between buccal and gingival mucosa | Slowly growing gingival mass | Local excision | – | – | No | No | N/D |
Miettinen M et al. (2008) [25] | 20 | 21–81 (median 50) | 62% M | 9 neck, 3 scalp, 1 lower lip, 7 various sites | Variable | Local excision | 0–41/50 HPFs | – | 22% (≥1) | No | 2–61 y (mean 13) |
Nonaka CF et al. (2009) [6] | 1 | 21 | F | R posterior mandibular gingiva | Painless exophytic mass | Local excision | – | – | No | No | 7 mo |
Graham RP et al. (2011) [33] | 9 | 39–63 (median 52) | 52% M | Head and neck, various sites | N/D | N/D | N/D | N/D | N/D | N/D | 12–149 mo |
Kondylidou-Sidira et al.(2011) [5] | 1 | 24 | M | Zygomatomaxillary buttress | Subcutaneous lump | Local excision | – | – | No | No | 2 y |
Gebre-Mehdin et al. (2012) [28] | 4 | 47 | F | Temple | N/D | N/D | – | – | No | No | N/D |
| Â | 59 | M | Neck | N/D | N/D | N/D | + | Yes (1) | Yes (rib) | N/D | |
| Â | 42 | M | Neck | N/D | N/D | N/D | + | No | No | N/D | |
| Â | 43 | M | Paralaryngeal | N/D | N/D | N/D | + | No | No | N/D | |
Ohta et al. (2013) [31] | 1 | 26 | M | Tongue | Painless mass | Local excision | > 2/10 HPFs | – | Yes (1) | No | 4 y |
Ottoman B (2015) [30] | 1 | 72 | M | L posterior maxilla | Exophytic mass | N/D | – | – | No | No | N/D |
Dantey K et al. (2016) [26] | 1 | 33 | M | Parotid region | Mass | Local excision | – | – | No | No | 3 y |
Case report | 1 | 52 | M | R submandibular region | Right neck swelling | Local excision | – | – | No | No | 6 mo |