Fig. 1

Follicular lymphoma case for representative demonstration (a-c) with H&E staining (a), BCl2 (b) and IgD (c) staining, respectively (Original magnification × 400). Representative morphologic and immunohistochemical findings of the in situ neoplasia case (c-e): Haematoxylin & Eosin (H&E) staining (d) and BCL2 immunohistochemistry (e) (Original magnification × 400). The chromosomal translocation t(14;18) was detectable in the in situ neoplasia cells using the FICTION technique (f) (Original magnification × 1000)