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Fig. 2 | Diagnostic Pathology

Fig. 2

From: The t(14;18) translocation is absent from endothelial and follicular dendritic cells of follicular lymphoma (FL) and shows heterogeneous presence in preserved FL mantle zones

Fig. 2

a, b FICTION technique: FISH method in combination with immunohistochemical IgD staining. Well identifiable hybridization signals in the IgD + cells as well as in the IgD - neighborhood, here with t(14;18) translocations (arrows) (Original magnification × 1000 (a,b). c FICTION with t(14;18) transcolations (arrows) in the vicinity of single or d clusters of CD34 stained cells, each without translocation t(14;18) (Original magnification × 600 (c,d)). e, f Combined FICTION method of simultaneously stained IgD (red) and clusterin (green) cells (f) (Original magnification: × 200/× 1000 (e,f) each). Arrows show translocated signals

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