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Fig. 5 | Diagnostic Pathology

Fig. 5

From: GSK-3β inhibits autophagy and enhances radiosensitivity in non-small cell lung cancer

Fig. 5

GSK-3β inhibition promoted cellular autophagy. Western blotting showed that (a) after X-ray irradiation alone, GSK-3β levels decreased; p62 and AMPK levels did not change significantly; and LC3 levels increased in A549 cells. After treatment with the GSK-3 inhibitor SB216763, p62 levels did not change significantly, whereas AMPK and LC3 levels increased. After treatment with the GSK-3β inhibitor SB216763 and X-ray irradiation, p62 and AMPK levels did not change significantly, whereas LC3 levels increased (b, c, d). *P < 0.05

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