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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Cervical small cell carcinoma frequently presented in multiple high risk HPV infection and often associated with other type of epithelial tumors

Fig. 3

HPV DNA detection using in situ hybridization (× 400). a Small cell carcinoma illustrated punctate staining pattern with one navy-blue puncta signal in the nuclei. b Multiple small puncta inside the nuclei of small cell carcinoma represents low viral copy number of HPV DNA. c Diffuse small particles were observed in the nuclei of small cell carcinoma. d Squamous cell carcinoma displayed punctuate signal patterns. e Squamous cell carcinoma illustrated episomal staining pattern. f Tumor cells of adenocarcinoma positive with one navy-blue puncta

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Diagnostic Pathology

ISSN: 1746-1596

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