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Fig. 5 | Diagnostic Pathology

Fig. 5

From: Cervical small cell carcinoma frequently presented in multiple high risk HPV infection and often associated with other type of epithelial tumors

Fig. 5

Immunohistochemical expression of p16 and p53 (× 400). Strong and diffuse nuclear and cytoplasmic staining for p16 was noted in cervical small cell carcinoma (a) and squamous cell carcinoma (b). c Nuclear staining for p53 was observed in cervical squamous cell carcinoma, wich revealed TP53 missense mutation. d Cervical small cell carcinoma illustrating scattered, weakly positive nuclear staining for p53 revealed wild type pattern of TP53

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