Fig. 5From: Cervical small cell carcinoma frequently presented in multiple high risk HPV infection and often associated with other type of epithelial tumorsImmunohistochemical expression of p16 and p53 (× 400). Strong and diffuse nuclear and cytoplasmic staining for p16 was noted in cervical small cell carcinoma (a) and squamous cell carcinoma (b). c Nuclear staining for p53 was observed in cervical squamous cell carcinoma, wich revealed TP53 missense mutation. d Cervical small cell carcinoma illustrating scattered, weakly positive nuclear staining for p53 revealed wild type pattern of TP53Back to article page