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Table 4 Hot spot values of Ki-67 LI for two raters

From: Evaluation of the proliferation marker Ki-67 in gliomas: Interobserver variability and digital quantification

Digital quantification

 

%

0

5

10

15

20

25

30

40

50

60

70

80

90

Total (n)

Pathologist A

0

4

    

1

       

5

5

1

2

4

  

1

       

8

10

 

9

6

1

1

1

 

1

  

1

  

20

15

 

2

3

5

6

1

3

4

     

24

20

   

6

5

2

4

2

     

19

25

1

 

1

1

4

4

5

6

     

22

30

 

2

2

2

5

7

14

10

2

1

   

45

40

   

2

4

4

10

19

6

5

   

50

50

 

1

  

1

1

3

12

8

2

2

  

30

60

       

1

1

3

1

1

 

7

70

       

1

 

1

2

  

4

80

          

1

  

1

90

              

Total (n)

6

16

16

17

26

22

39

56

17

12

7

1

 

235

κ

 

0.21

SE κ

 

0.02

Pathologist B

0

4

1

3

 

1

2

 

1

     

12

5

1

12

6

2

1

  

1

     

23

10

  

5

7

7

4

2

2

  

1

  

28

15

  

1

6

10

6

5

11

     

39

20

 

1

1

1

2

5

23

9

3

2

   

47

25

1

2

  

3

3

6

8

2

3

   

28

30

   

1

1

 

2

18

7

4

1

  

34

40

     

2

1

5

2

2

1

  

13

50

    

1

   

3

1

2

1

 

8

60

              

70

              

80

       

1

  

1

  

2

90

          

1

  

1

Total (n)

6

16

16

17

26

22

39

56

17

12

7

1

 

235

κ

 

0.09

SE κ

 

0.02

  1. n Number of cases
  2. SE Standard error
  3. Cases marked in bold indicate agreement
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Diagnostic Pathology

ISSN: 1746-1596

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