|
Clinicopathological parameters
|
Calpain II expression
|
|---|
|
Positive (%) n = 64
|
Negative (%) n = 19
|
P value
|
|---|
|
ER
| | |
0.580
|
|
Positive
|
35 (54.7)
|
9 (47.4)
| |
|
Negative
|
29 (45.3)
|
10 (52.6)
| |
|
HER2
| | |
0.597
|
|
Positive
|
21 (32.8)
|
5 (26.3)
| |
|
Negative
|
43 (67.2)
|
14 (73.7)
| |
|
pAKT
| | |
0.029
a
|
|
Positive
|
50 (78.1)
|
10 (52.6)
| |
|
Negative
|
14 (21.9)
|
9 (47.4)
| |
|
pmTOR
| | |
0.011
a
|
|
Positive
|
52 (81.3)
|
10 (52.6)
| |
|
Negative
|
12 (18.8)
|
9 (47.4)
| |
|
p4E-BP1
| | |
< 0.001
a
|
|
Positive
|
52 (81.3)
|
6 (31.6)
| |
|
Negative
|
12 (18.8)
|
13 (68.4)
| |
|
p-p70S6K
| | |
0.003
a
|
|
Positive
|
52 (81.3)
|
9 (47.4)
| |
|
Negative
|
12 (18.8)
|
10 (52.6)
| |
|
Stage
| | |
0.773
|
|
Stage I
|
7 (10.9)
|
1 (5.3)
| |
|
Stage II
|
37(57.8)
|
14 (73.7)
| |
|
Stage III
|
20 (31.3)
|
4 (21.2)
| |
|
Grade
| | |
0.568
|
|
Grade I
|
16 (25.0)
|
3 (15.8)
| |
|
Grade II
|
35 (54.7)
|
12 (63.2)
| |
|
Grade III
|
13 (20.3)
|
4 (21.1)
| |
|
Nodal status
| | |
0.876
|
|
Positive
|
45 (70.3)
|
13 (68.4)
| |
|
Negative
|
19 (29.7)
|
6 (31.6)
| |
|
Distant metastasis
| | |
0.122
|
|
Positive
|
26 (40.6)
|
4 (21.1)
| |
|
Negative
|
38 (59.4)
|
15 (78.9)
| |
|
Tumor size
| | |
0.013
a
|
| ≦4 cm |
34 (53.1)
|
4 (21.1)
| |
|
> 4 cm
|
30 (46.9)
|
15 (78.9)
| |
|
Age
| | |
0.653
|
| ≦55 yrs |
44 (68.8)
|
12 (63.2)
| |
|
> 55 yrs
|
20 (31.3)
|
7 (36.8)
| |
- aStatistically significant p values are in bold
