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Table 3 The correlation between calpain II expression and clinicopathological parameters in IDC cases

From: Cytoplasmic FOXP1 expression is correlated with ER and calpain II expression and predicts a poor outcome in breast cancer

Clinicopathological parameters Calpain II expression
Positive (%) n = 64 Negative (%) n = 19 P value
ER    0.580
 Positive 35 (54.7) 9 (47.4)  
 Negative 29 (45.3) 10 (52.6)  
HER2    0.597
 Positive 21 (32.8) 5 (26.3)  
 Negative 43 (67.2) 14 (73.7)  
pAKT    0.029 a
 Positive 50 (78.1) 10 (52.6)  
 Negative 14 (21.9) 9 (47.4)  
pmTOR    0.011 a
 Positive 52 (81.3) 10 (52.6)  
 Negative 12 (18.8) 9 (47.4)  
p4E-BP1    < 0.001 a
 Positive 52 (81.3) 6 (31.6)  
 Negative 12 (18.8) 13 (68.4)  
p-p70S6K    0.003 a
 Positive 52 (81.3) 9 (47.4)  
 Negative 12 (18.8) 10 (52.6)  
Stage    0.773
 Stage I 7 (10.9) 1 (5.3)  
 Stage II 37(57.8) 14 (73.7)  
 Stage III 20 (31.3) 4 (21.2)  
Grade    0.568
 Grade I 16 (25.0) 3 (15.8)  
 Grade II 35 (54.7) 12 (63.2)  
 Grade III 13 (20.3) 4 (21.1)  
Nodal status    0.876
 Positive 45 (70.3) 13 (68.4)  
 Negative 19 (29.7) 6 (31.6)  
Distant metastasis    0.122
 Positive 26 (40.6) 4 (21.1)  
 Negative 38 (59.4) 15 (78.9)  
Tumor size    0.013 a
4 cm 34 (53.1) 4 (21.1)  
 > 4 cm 30 (46.9) 15 (78.9)  
Age    0.653
55 yrs 44 (68.8) 12 (63.2)  
 > 55 yrs 20 (31.3) 7 (36.8)  
  1. aStatistically significant p values are in bold