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Table 4 Univariate analysis and multivariate analysis of factors affecting lymph node metastasis

From: Evaluation of the correlation of MACC1, CD44, Twist1, and KiSS-1 in the metastasis and prognosis for colon carcinoma

Variables

Categories

Univariate analysis

Multivariate analysis

P

HR

95% CI

P

Invasion

Subserosa/ Visceral peritoneuma

< 0.001

12.336

1.264-120.427

0.031

MACC1

Negative/Positive

< 0.001

2.956

1.222–7.149

0.016

CD44

Negative/Positive

< 0.001

6.496

2.858–14.767

< 0.001

Twist1

Negative/Positive

< 0.001

3.951

1.673–9.331

0.002

KiSS-1

Negative/Positive

< 0.001

0.271

0.110–0.666

0.004

  1. aSubserosa: The tumor has grown through the mucosa and into the subserosa; Visceral peritoneum: The tumor has grown into the surface of the visceral peritoneum, which means it has grown through all layers of the colon, or the tumor has grown into or has attached to other organs or structures