From: Novel clinicopathological and molecular characterization of metanephric adenoma: a study of 28 cases
Patient Number | BRAF status | CK7 | AMACR | WT-1 | CD57 | P53 | BCL2 | CCND1 | P16 | p-ERK | ERK | p-MEK | MEK | DUSP6 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | BRAF V600E | – | – | 3+ | 2+ | – | 3+ | – | 3+ | – | 3+ | 2+ | 3+ | 2+ |
2 | BRAF wild-type | – | – | 3+ | 3+ | – | – | – | 2+ | – | 3+ | 2+ | 3+ | 1+ |
3 | BRAF V600E | – | – | 1+ | 2+ | – | – | – | 1+ | – | 2+ | 1+ | 2+ | 1+ |
4 | BRAF wild-type | – | – | 2+ | 2+ | – | – | – | 1+ | – | 2+ | 1+ | 3+ | – |
5 | BRAF V600E | – | – | 3+ | 3+ | – | 1+ | – | – | – | 3+ | 2+ | 3+ | 1+ |
6 | BRAF V600E | – | – | 3+ | 2+ | – | – | – | 1+ | – | 2+ | 1+ | 2+ | 1+ |
7 | BRAF V600E | – | – | 1+ | 2+ | – | 2+ | – | 2+ | 1+ | 1+ | 1+ | 2+ | 1+ |
8 | BRAF V600E | – | – | 2+ | 2+ | – | 2+ | – | 2+ | – | 2+ | 1+ | 3+ | – |
9 | BRAF V600E | – | – | 3+ | 3+ | – | 3+ | – | 2+ | 1+ | 2+ | 1+ | 3+ | 1+ |
10 | BRAF V600E | – | – | 1+ | 3+ | – | 2+ | – | 2+ | 1+ | 1+ | 1+ | 3+ | 2+ |
11 | BRAF V600E | – | – | 3+ | 2+ | – | 3+ | – | 3+ | 1+ | 2+ | 1+ | 2+ | 2+ |
12 | BRAF V600E | – | – | – | 3+ | – | 3+ | – | 3+ | – | 2+ | 2+ | 1+ | 2+ |
13 | BRAF V600E | – | – | 2+ | – | – | 3+ | – | 2+ | 1+ | 1+ | 1+ | 2+ | 1+ |
14 | BRAF V600E | – | – | 3+ | 2+ | 2+ | – | 1+ | 1+ | 1+ | 1+ | 2+ | 1+ | |
15 | BRAF V600E | – | – | – | 1+ | – | 3+ | – | 1+ | – | 2+ | 2+ | 1+ | 2+ |
16 | BRAF V600E | – | – | 1+ | 1+ | – | 2+ | – | 1+ | – | 1+ | 2+ | 3+ | – |
17 | BRAF wild-type | – | – | 1+ | 1+ | – | – | – | – | 1+ | 2+ | 1+ | 3+ | 1+ |
18 | BRAF V600E | – | – | 1+ | 1+ | – | 3+ | – | 3+ | – | 3+ | 1+ | 3+ | 1+ |
19 | BRAF V600E | – | – | – | 1+ | – | 3+ | – | 2+ | – | 3+ | 1+ | 1+ | 2+ |
20 | BRAF Intron8-STARD9/ CUX1/ LOC100507389 fusion | +/− | – | 1+ | 1+ | – | 3+ | – | 3+ | 1+ | 2+ | 1+ | 2+ | 1+ |
21 | BRAF V600E | – | – | 1+ | 1+ | – | 2+ | – | 1+ | – | 1+ | 1+ | 3+ | 1+ |
22 | BRAF V600E | – | – | 1+ | 1+ | – | 3+ | – | 1+ | 1 | 1+ | 1+ | 2+ | 1+ |
23 | BRAF V600E | +/− | 1+ | 1+ | 1+ | – | 3+ | – | 2+ | 1 | 1+ | 1+ | 2+ | 1+ |
24 | BRAF wild-type | – | – | 1+ | 1+ | – | 2+ | – | – | 1+ | 2+ | 1+ | 1+ | 1+ |
25 | BRAF wild-type | – | – | 1+ | 1+ | – | 3+ | – | – | 1+ | 3+ | 2+ | 2+ | – |
26 | BRAF V600E | – | – | 1+ | 1+ | – | 3+ | – | 1+ | – | 3+ | 1+ | 3+ | 2+ |
27 | BRAF V600E | – | – | 1+ | 1+ | – | 2+ | – | 2+ | – | 1+ | 1+ | 3+ | 1+ |
28 | BRAF V600E | – | – | 1+ | 1+ | – | 3+ | – | 1+ | 1+ | 1+ | 1+ | 1+ | 1+ |