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Table 1 Clinicopathological characteristics of 30 MFS cases

From: MET-overexpressing myxofibrosarcoma frequently exhibit polysomy of chromosome 7 but not MET amplification, especially in high-grade cases: clinical and pathological review of 30 myxofibrosarcoma cases

Case

Age

(≥56)

Gender

Location

Tumor size(cm)

FNCLCC grade

MET expression

chromosome 7 polysomy

Ki67

Index

Follow-up

1

Y

F

Left leg

4.5

Grade 2

+

+

40%

local recurrence

2

N

M

Left ischium

8

Grade 2

20%

NED

3

Y

M

Right shoulder

2.2

Grade 2

15%

NED

4

Y

F

Left leg

1.8

Grade 1

15%

NED

5

Y

F

Right shoulder

5

Grade 3

+

+

45%

local recurrence

6

N

M

Right leg

1

Grade 2

15%

seven months later, die of metastasis

7

N

M

Back

3.5

Grade 3

+

+

30%

local recurrence

8

N

F

Left leg

3

Grade 1

3%

NED

9

Y

F

Left scapula

11

Grade 3

+

+

40%

local recurrence and metastasis to axillary

10

N

M

Right forearm

4

Grade 1

5%

NED

11

Y

F

Right leg

1.5

Grade 1

3%

NED

12*

N

M

Right foot

1.8

Grade 1

6%

NED

13*

N

F

Ankle

4

Grade 2

+

+

15%

N/D

14

N

F

Left leg

21

Grade 2

40%

N/D

15

Y

M

Right armpit

4.5

Grade 2

40%

N/D

16

N

F

Left arm

1.8

Grade 1

+

+

10%

N/D

17

Y

M

Left shoulder

4

Grade 2

+

80%

N/D

18

Y

M

Right arm

4

Grade 3

+

+

70%

N/D

19

Y

F

Right leg

19

Grade 3

+

+

20%

N/D

20

N

M

Left leg

7.5

Grade 3

+

70%

N/D

21

Y

M

Right chest wall

19

Grade 2

60%

N/D

22

N

M

Right chest wall

1.5

Grade 2

60%

N/D

23

Y

M

Left arm

11

Grade 3

+

+

70%

local recurrence

24

Y

M

Left leg

13

Grade 3

60%

N/D

25

Y

M

Right arm

6

Grade 3

+

+

40%

N/D

26

N

F

Left shoulder

11

Grade 3

50%

local recurrence

27

Y

F

Right leg

9

Grade 3

+

+

20%

N/D

28

Y

F

Right leg

9

Grade 2

60%

N/D

29

Y

M

Left leg

2

Grade 2

40%

local recurrence

30

Y

F

Neck

3.5

Grade 3

+

40%

N/D

  1. *: epithelioid variant NED no evidence of disease. N/D not done