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Table 2 Clinicopathological characteristics and associations with MET immunoexpression and chrosome 7 polysomy in 30 MFS

From: MET-overexpressing myxofibrosarcoma frequently exhibit polysomy of chromosome 7 but not MET amplification, especially in high-grade cases: clinical and pathological review of 30 myxofibrosarcoma cases

Parameters

C-MET expression

P

(CEP7 polysomy)

P

+

+

Age

  

0.232

  

0.757

  ≥ 56

10

8

 

7

11

 

 <56

4

8

 

4

8

 

Gender

  

0.282

  

0.156

 Male

6

10

 

4

12

 

 Female

8

6

 

7

7

 

Tumor size

  

0.812

  

0.892

  ≥ 6.7

5

6

 

4

7

 

 <6.7

9

9

 

7

11

 

Location

  

0.765

  

0.757

 limbs

8

10

 

7

11

 

 other

6

6

 

4

8

 

FNCLCC grade

  

0.004

  

0.021*

 Grade 1

1

5

 

1

5

 

 Grade 2

3

9

 

2

10

 

 Grade 3

10

2

 

8

4

 

Ki-67 Index

  

0.011

  

0.029*

  ≥ 0.33

10

4

 

8

6

 

 <0.33

4

12

 

3

13

 

Local recurrence and metastasisa

  

0.010

  

0.010*

 Yes

5

3

 

5

3

 

 No

0

7

 

0

7

 
  1. *p<0.05 is considerably significantlly. a:n = 15, half of the cases were censored