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Table 2 PD-1, CD4, CD8, HIF-1α, and HIF-2α expression according to PD-L1 results

From: Prognostic significance of the programmed death ligand 1 expression in clear cell renal cell carcinoma and correlation with the tumor microenvironment and hypoxia-inducible factor expression

  

PD-L1 Staining

Test Statistics (χ2; P)

Negative n (%)

Positive n (%)

PD-1

Mild

92 (73.6)

6 (30.0)

14.961; 0.000

Dense

33 (26.4)

14 (70.0)

CD4

Mild

64 (51.2)

2 (10.0)

11.801; 0.001

Dense

61 (48.8)

18 (90.0)

CD8

Mild

66 (52.8)

2 (10.0)

12.682; 0.000

Dense

59 (47.2)

18 (90.0)

HIF-1α

Low

55 (44.0)

11 (55.0)

0.841; 0.359

High

70 (56.0)

9 (45.0)

HIF-2α

Low

57 (45.6)

4 (20.0)

4.636; 0.031

High

68 (54.4)

16 (80.0)