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Fig. 1 | Diagnostic Pathology

Fig. 1

From: Detection of specific gene rearrangements by fluorescence in situ hybridization in 16 cases of clear cell sarcoma of soft tissue and 6 cases of clear cell sarcoma-like gastrointestinal tumor

Fig. 1

Pathological findings of CCSST with EWSR1 and ATF1 rearrangements. a CCSSTs showed sheet-like and nested growth patterns of polyhedral tumor cells (200×). b Tumor cells had round nuclei with conspicuous nucleoli and clear to pale eosinophilic cytoplasm (400×). c FISH of EWSR1 split signals. Tumor cells showed EWSR1 split signal with a pair of fused (arrow) and split (arrow head) patterns (1000×). d FISH of ATF1 split signals. Tumor cells showed EWSR1 split signal with a pair of fused (arrow) and split (arrow head) patterns (1000×)

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