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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Detection of specific gene rearrangements by fluorescence in situ hybridization in 16 cases of clear cell sarcoma of soft tissue and 6 cases of clear cell sarcoma-like gastrointestinal tumor

Fig. 2

Pathological findings of CCSST with EWSR1 and CREM rearrangements. a Metastatic CCSST of the lymph nodes (100×). b Tumor cells were polyhedral to spindle-shaped and had oval to round nuclei with pale to clear and eosinophilic cytoplasm (400×). c FISH of EWSR1 split signals. Tumor cells showed EWSR1 split signal with a pair of fused (arrow) and split (arrow head) patterns (1000×). d FISH of CREM split signals. Tumor cells showed CREM split signal with a pair of fused (arrow) and split (arrow head) patterns (1000×)

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