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Table 6 The multivariate Cox proportional- hazards regression for OS

From: Overexpression of the recently identified oncogene REDD1 correlates with tumor progression and is an independent unfavorable prognostic factor for ovarian carcinoma

   95.0% CI for Exp(B)
B SE Wald df P-value Exp(B) Lower Upper
Age(years)
< 40    12.931 2 0.002    
40–60 −1.99 0.594 11.217 1 0.001 0.137 0.043 0.438
≥ 60 −2.096 0.585 12.82 1 < 0.001 0.123 0.039 0.387
Histologic type
 Serous carcinoma    12.222 4 0.016    
 Mucinous carcinoma 1.813 0.785 5.331 1 0.021 6.13 1.315 28.57
 Endometrioid carcinoma 0.014 0.385 0.001 1 0.972 1.014 0.476 2.158
 Clear-cell carcinoma 1.722 0.634 7.366 1 0.007 5.593 1.613 19.391
 Mixed-type carcinoma −0.121 0.415 0.085 1 0.771 0.886 0.393 1.997
Ascites
 No    6.469 2 0.039    
 Yes 0.444 0.291 2.336 1 0.126 1.559 0.882 2.756
 Unknown −1.378 0.796 2.999 1 0.083 0.252 0.053 1.199
Stage (II-IVvsI) 1.554 .338 21.096 1 < 0.001 4.729 2.437 9.177
cytoplasmic REDD1 expression 1.201 0.318 14.23 1 < 0.001 3.325 1.781 6.206
  1. Dependent variable: overall survival
  2. Independent variables: age, stage, histologic type, ascites, serum CA125 level, chemotherapy response, cytoplasmic REDD1 expression
  3. B:regression coefficient, SE:standard error, Wald:Wald chi square, Df: degree of freedom