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Table 6 The multivariate Cox proportional- hazards regression for OS

From: Overexpression of the recently identified oncogene REDD1 correlates with tumor progression and is an independent unfavorable prognostic factor for ovarian carcinoma

  

95.0% CI for Exp(B)

B

SE

Wald

df

P-value

Exp(B)

Lower

Upper

Age(years)

< 40

  

12.931

2

0.002

   

40–60

−1.99

0.594

11.217

1

0.001

0.137

0.043

0.438

≥ 60

−2.096

0.585

12.82

1

< 0.001

0.123

0.039

0.387

Histologic type

 Serous carcinoma

  

12.222

4

0.016

   

 Mucinous carcinoma

1.813

0.785

5.331

1

0.021

6.13

1.315

28.57

 Endometrioid carcinoma

0.014

0.385

0.001

1

0.972

1.014

0.476

2.158

 Clear-cell carcinoma

1.722

0.634

7.366

1

0.007

5.593

1.613

19.391

 Mixed-type carcinoma

−0.121

0.415

0.085

1

0.771

0.886

0.393

1.997

Ascites

 No

  

6.469

2

0.039

   

 Yes

0.444

0.291

2.336

1

0.126

1.559

0.882

2.756

 Unknown

−1.378

0.796

2.999

1

0.083

0.252

0.053

1.199

Stage (II-IVvsI)

1.554

.338

21.096

1

< 0.001

4.729

2.437

9.177

cytoplasmic REDD1 expression

1.201

0.318

14.23

1

< 0.001

3.325

1.781

6.206

  1. Dependent variable: overall survival
  2. Independent variables: age, stage, histologic type, ascites, serum CA125 level, chemotherapy response, cytoplasmic REDD1 expression
  3. B:regression coefficient, SE:standard error, Wald:Wald chi square, Df: degree of freedom