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Table 7 The multivariate Cox proportional- hazards regression for DFS

From: Overexpression of the recently identified oncogene REDD1 correlates with tumor progression and is an independent unfavorable prognostic factor for ovarian carcinoma

   95% CI for Exp(B)
B SE Wald df P-value Exp(B) Lower Upper
Age (years)
  < 40    1.562 2.000 0.458 1.000   
 40–60 0.488 0.394 1.536 1.000 0.215 1.629 0.753 3.524
  ≥ 60 0.040 0.229 0.031 1.000 0.860 1.041 0.665 1.629
Histologic type
 Serous carcinoma    16.706 3.000 0.001 1.000   
 Mucinous carcinoma 0.380 0.450 0.713 1.000 0.399 1.462 0.605 3.533
 Endometrioid carcinoma 1.953 0.587 11.065 1.000 0.001 7.053 2.231 22.297
 Clear-cell carcinoma 1.192 0.700 2.900 1.000 0.089 3.292 0.835 12.972
 Mixed-type carcinoma 0.656 0.483 1.844 1.000 0.174 1.926 0.748 4.961
Response to chemotherapy
 Completely Responders    17.056 3.000 0.001 1.000   
 Partial responders 1.885 0.503 14.051 1.000 0.000 6.584 2.458 17.639
 Non-responders 0.956 0.656 2.120 1.000 0.145 2.600 0.718 9.412
 Unknown response −0.839 0.672 1.559 1.000 0.212 0.432 0.116 1.613
Stage (II-IVvsI) 0.904 0.312 8.361 1.000 0.004 2.468 1.338 4.554
Cytoplasmic REDD1 expression −1.479 0.295 25.102 1.000 < 0.001 0.228 0.128 0.407
  1. Dependent variable: disease-free survival time
  2. Independent variables: age, stage, histologic type, ascites, serum CA125 level, stage, chemotherapy response, and cytoplasmic REDD1 expression
  3. B: regression coefficient, SE: standard error, Wald: Wald error, Wald: Wald chi square, Df: degree of freedom