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Table 7 The multivariate Cox proportional- hazards regression for DFS

From: Overexpression of the recently identified oncogene REDD1 correlates with tumor progression and is an independent unfavorable prognostic factor for ovarian carcinoma

  

95% CI for Exp(B)

B

SE

Wald

df

P-value

Exp(B)

Lower

Upper

Age (years)

  < 40

  

1.562

2.000

0.458

1.000

  

 40–60

0.488

0.394

1.536

1.000

0.215

1.629

0.753

3.524

  ≥ 60

0.040

0.229

0.031

1.000

0.860

1.041

0.665

1.629

Histologic type

 Serous carcinoma

  

16.706

3.000

0.001

1.000

  

 Mucinous carcinoma

0.380

0.450

0.713

1.000

0.399

1.462

0.605

3.533

 Endometrioid carcinoma

1.953

0.587

11.065

1.000

0.001

7.053

2.231

22.297

 Clear-cell carcinoma

1.192

0.700

2.900

1.000

0.089

3.292

0.835

12.972

 Mixed-type carcinoma

0.656

0.483

1.844

1.000

0.174

1.926

0.748

4.961

Response to chemotherapy

 Completely Responders

  

17.056

3.000

0.001

1.000

  

 Partial responders

1.885

0.503

14.051

1.000

0.000

6.584

2.458

17.639

 Non-responders

0.956

0.656

2.120

1.000

0.145

2.600

0.718

9.412

 Unknown response

−0.839

0.672

1.559

1.000

0.212

0.432

0.116

1.613

Stage (II-IVvsI)

0.904

0.312

8.361

1.000

0.004

2.468

1.338

4.554

Cytoplasmic REDD1 expression

−1.479

0.295

25.102

1.000

< 0.001

0.228

0.128

0.407

  1. Dependent variable: disease-free survival time
  2. Independent variables: age, stage, histologic type, ascites, serum CA125 level, stage, chemotherapy response, and cytoplasmic REDD1 expression
  3. B: regression coefficient, SE: standard error, Wald: Wald error, Wald: Wald chi square, Df: degree of freedom