Table 2 Summary of Variants with Possible or Unknown Significance Present in Follicular Lymphoma or/and Langerhans Cell Sarcoma
From: KRAS mutation in secondary malignant histiocytosis arising from low grade follicular lymphoma
Variants Shared in FL and LCS | Variants present only in FL | Variants present only in LCS |
|---|---|---|
10 nonsynonymous SNVs  SPEN p.K1064I  PDE4DIP p.R1867C  PDE4DIP p.E573V  PDE4DIP p.S438 L  PDE4DIP p.A127T  ARHGAP26 p.R293W  PMS2 p.I18V  ATM p.S49C  KMT2D p.P1131L  SPECC1 p.D688N | 4 nonsynonymous SNVs  IL2 p.V89 L  CDKN2A p.M1T  BCL2 p.S203 N  BCL2 p.A45T  SMARCA4 p.G883D | 11 nonsynonymous SNVs  BIN1 p.H283Y  TMEM200A p.G383R  DNAJB12 p.R13W  KRAS p.G13D  TRPV42 p.R249H  ADAD2 p.R299Q  KRTAP4–7 p.S113C  EMR2 p.C520F  ARMCX4 p.G1814E  ARMCX4 p.E1816G  ARMCX4 p.G1820E |
2 inframe deletions  ZNF384 p.385_385del  CREBBP p.1640_1641del | 1 stopgain  KMT2D p.R5097X | 2 frameshift insertions  CAMTA1 p.N1271 fs  BCR p.G1049 fs |
|  | 3 inframe deletions  MLLT3  MN1 p.524_524del  MN1 p.304_304del | 2 inframe deletions  ARID1A p.1333_1334del  NOTCH1 p.2411_2411del |