Table 3 Chromosomal abnormalities in Follicular lymphoma and Langerhans cell sarcoma detected by SNP microarray
From: KRAS mutation in secondary malignant histiocytosis arising from low grade follicular lymphoma
Sample | Type | Chromosome | Cytoband | Size (Mb) | Comment |
|---|---|---|---|---|---|
Follicular Lymphoma | Loss | 6 | q11.1-q27 | 109.02 | Â |
9 | p21 | 0.74 | CDKN2A gene | ||
10 | q24.1 | 1.43 | Â | ||
16 | p13.3-p13.12 | 14.25 | Â | ||
Homozygous loss | 22q | q11.22 | 0.5 | IGL gene | |
Gain | 7 | p21.1-p15.3 | 4.18 | Â | |
16 | p11.2 | 1.01 | Â | ||
20 | p12.2-p12.1 | 4.52 | Â | ||
20 | p11.23-q13.33 | 44.31 | Â | ||
X | p22.33-q28 | 155.27 | Whole chromosome gain | ||
High copy gain | 22 | q11.23 | 0.05 | CNV | |
CN-LOH | 6 | p25.3-p11.1 | 58.73 | Â | |
20 | p13-p12.2 | 9.45 | Â | ||
20 | p12.1-p11.23 | 5.06 | Â | ||
Langerhans cell sarcoma | Point mutation | 12 | p12.1 | – | p.G13D c.38G > A |
High copy gain | 22 | q11.23 | 0.05 | CNV |