Fig. 2From: Robustness of biomarker determination in breast cancer by RT-qPCR: impact of tumor cell content, DCIS and non-neoplastic breast tissueEffect of adipose tissue on relative gene expression. Shown in the graph are gene expression data of n = 10 breast cancer specimen for ERBB2(a), ESR1 (b), PGR (c) and MKI67 (d) in whole sections (over 50% adipose tissue content, green circles) versus tumor-enriched sections (blue squares). Dotted lines represent the respective cut-off for the four marker genes (ERBB2: 41.10; ESR1: 38.00; PGR: 35.50; MKI67: 35.90)Back to article page