Fig. 3

Effect of normal tissue and TCC on relative gene expression. a Representative images of sample number 9 (left) and sample number 3 (right) before and after microdissection of the respective tumor area (encircled in orange). b-e Shown in the graph are gene expression data of n = 15 breast cancer specimen for ERBB2(b), ESR1 (c), PGR (d) and MKI67 (e) in whole sections (green circles) versus tumor-enriched sections (blue squares). Dotted lines represent the respective cut-off for the four marker genes (ERBB2: 41.10; ESR1: 38.00; PGR: 35.50; MKI67: 35.90)