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Table 1 Differences in MammaTyper® relative gene expression between pairs of whole tissue and tumor-enriched specimens

From: Robustness of biomarker determination in breast cancer by RT-qPCR: impact of tumor cell content, DCIS and non-neoplastic breast tissue

Tumor cell content Mean (min, max) absolute difference of 40-ddCq of paired measurements
ERBB2 ESR1 PGR MKI67
20–39% 0.49 (0.04 to 0.86) 0.34 (0.01 to 0.80) 0.39 (0.15 to 0.72) 0.58 (0.17 to 1.46)
40–59% 0.38 (0.11 to 0.65) 0.53 (0.08 to 1.15) 0.49 (0.28 to 0.68) 0.58 (0.33 to 1.28)
60–79% 0.24 (0.15 to 0.30) 0.40 (0.22 to 0.50) 0.16 (0.04 to 0.23) 0.09 (0.01 to 0.23)