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Table 1 Differences in MammaTyper® relative gene expression between pairs of whole tissue and tumor-enriched specimens

From: Robustness of biomarker determination in breast cancer by RT-qPCR: impact of tumor cell content, DCIS and non-neoplastic breast tissue

Tumor cell content

Mean (min, max) absolute difference of 40-ddCq of paired measurements

ERBB2

ESR1

PGR

MKI67

20–39%

0.49 (0.04 to 0.86)

0.34 (0.01 to 0.80)

0.39 (0.15 to 0.72)

0.58 (0.17 to 1.46)

40–59%

0.38 (0.11 to 0.65)

0.53 (0.08 to 1.15)

0.49 (0.28 to 0.68)

0.58 (0.33 to 1.28)

60–79%

0.24 (0.15 to 0.30)

0.40 (0.22 to 0.50)

0.16 (0.04 to 0.23)

0.09 (0.01 to 0.23)