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Fig. 3 | Diagnostic Pathology

Fig. 3

From: MYO18B promotes hepatocellular carcinoma progression by activating PI3K/AKT/mTOR signaling pathway

Fig. 3

Knockdown of MYO18B inhibited the proliferation, migration and invasion of HepG2 cells. a CCK-8 assays were performed to measure the proliferation of the transfected HepG2 cells, which showed knockdown of MYO18B (si-MYO18B group) obviously inhibited the cell growth. b, c Colony formation assays were used to determined the proliferation of the transfected HepG2 cells, which also revealed knockdown of MYO18B (si-MYO18B group) obviously inhibited the cell growth. d After incubated the transfected cells for 24 h, knockdown of MYO18B (si-MYO18B group) significantly suppressed the migration of HepG2 cells analyzed by wound healing assays. e, f Transwell assays further demonstrated that knockdown of MYO18B (si-MYO18B group) obviously inhibited the migration and invasion of the transfected HepG2 cells. *P < 0.05 versus si-con group

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