Fig. 1
From: Pathological characteristics and genetic features of melanin-producing medullary thyroid carcinoma
Morphological characteristics of melanin-producing MTC. H&E staining evidenced that the tumor cell with abundant black or brown melanin (a), minimal melanin (b). Melanin was found in the cytoplasm of the tumor cells or the extracellular matrix (c). The tumor displayed different structural morphologies: papillary (1d), microcapsule (1e), and angioneoplasm-like (1f). Part of the tumor cells were separated by amyloid-like material (1g). Psammoma bodies (1h) and tumor embolus (1I) was observed in certain visual fields, (hematoxylin-eosin staining, Magnification × 20)