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Table 4 Dendrin expression pattern in relation to pathohistological and clinical parameters

From: Expression of DENDRIN in several glomerular diseases and correlation to pathological parameters and renal failure - preliminary study

Parameter Pattern of dendrin expression in 33 patients with glomerular diseases P a
Nuclear (N = 9) Dual (N = 16) Negative (N = 8)
Interstitial fibrosis 0.05 (0.00–0.35) 0.01 (0.00–0.20) 0.10 (0.00–0.20) 0.024
Tubular atrophy 0.01 (0.00–0.35) 0.01 (0.00–0.20) 0.10 (0.01–0.25) 0.017
Globally sclerotic glomeruli 0.04 (0.00–0.35) 0.00 (0.00–0.21) 0.17 (0.00–0.50) 0.056
Creatinine clearance at the time of biopsy (ml/min/1.73m2)b 53 (27–118) 108 (25–212) 58 (27–150) 0.073
Creatinine clearance at the last follow-up (ml/min/1.73m2)b 68 (10–109) 91 (17–180) 11.5 (6–95) 0.009
Proteinuria (mg/dU/24 h)b 6380 (1460–18,677) 5375 (100–28,254) 4150 (63–5250) 0.208
  1. aKruskal-Wallis test
  2. bMedian (min-max)
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Diagnostic Pathology

ISSN: 1746-1596

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