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Table 1 Important virulence factors found in bacterial outer membrane vesicles

From: Bacterial outer membrane vesicles, a potential vaccine candidate in interactions with host cells based

Parent bacterium

Classification

Virulence factors

Description

Putative functions

References

Pasteurella multocida

Gram negative

β-lactamase (only found in Pm12945) OmpA, OmpH, OmpW, Tbp

Enzymes Proteins DNA

Disease pathogenesis, Deliver drug- resistant gene

16

Myxococcus xanthu

Gram negative

MepA, Several molecules with antibiotic properties, Hydrolytic enzymes

Proteins Enzymes

Hydrolytic function, antibiotic activities

17

Bacteroides fragilis

Gram negative

B.fragilis toxin (BFT).

protease

toxin packaging and delivery

18

Vibrio cholerae

Gram negative

VrrA, OmpA

RNA, Proteins

OMVs regulation

19

Bacillus subtilis

Gram positive

Lipoproteins, siderophore-binding proteins

Proteins

biosynthesis

20

Enterohemorrhagic Escherichia coli (EHEC)

Gram negative

Shiga toxin 2a, cytolethal distending toxin V, EHEC hemolysin, flagellin

Proteins

cell cycle arrest and pathogenesis

21