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Fig. 1 | Diagnostic Pathology

Fig. 1

From: Molecular characterization of sessile serrated adenoma/polyps with dysplasia/carcinoma based on immunohistochemistry, next-generation sequencing, and microsatellite instability testing: a case series study

Fig. 1

Typical morphologies in a representative case of sessile serrated adenoma/polyp (SSA/P) with submucosal carcinoma (Case #6). a Dilated crypts with deep serration was seen on both sides of the lesion, and high-grade dysplasia with submucosal invasion was seen in the middle. b High-power field of (a) (the left side). Crypts with a serrated architecture included those that were irregularly dilated, irregularly branched, and horizontally arranged (basal), corresponding to SSA/P. c High-power field of (a) (the middle). Well-differentiated tubular adenocarcinoma was observed invading the submucosa. Adjacent SSA/P areas were observed towards both sides of the panel. An abrupt transition was evident between the 2 adjacent regions

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Diagnostic Pathology

ISSN: 1746-1596

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