Fig. 1
From: Erdheim Chester disease in a patient with Burkitt lymphoma: a case report and review of literature
(a) Bone marrow biopsy shows cellular bone marrow with trilineage hematopoiesis and patchy, atypical histiocytic aggregates (H&E, 20x) (b) Atypical histiocytic aggregates are comprised of epithelioid to spindled-appearing histiocytes with a subset of foamy histiocytes (H&E, 400x). The atypical histiocytes are diffusely positive for (c) CD68 (200X) (d) Factor XIIIa (200x), and (e) BRAF V600E (clone VE1) and negative for (f) CD1a