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Table 1 Summary of immunohistochemical staining pattern for ECD differential diagnoses

From: Erdheim Chester disease in a patient with Burkitt lymphoma: a case report and review of literature

 

ECD

LCH

ICH

RDD

JXG

CD68

+

+

+/−

+

+

CD163

+

+

+/−

+

+

FXIIIa

+

–

–

–

+

CD1a

–

+

+

–

–

CD207 (Langerin)

–

+

–

–

–

S100

+/−

+

+

+

–

CD4

+

+

+

+

+

Lysozyme

+

+

+

+

+

BRAFV600E

+/−

+/−

+/−

–

+/−

  1. ECD Erdheim Chester Disease, ICH Indeterminate cell histiocytosis, JXG Juvenile xanthogranuloma, LCH Langerhans Cell Histiocytosis, RDD Rosai-Dorfman Disease