Skip to main content

Table 6 Multivariate Cox analysis to determine independent factors associated with patient survival for PD-L1 expression in tumor cells

From: PD-L1 expression and its clinicopathological correlation in advanced esophageal squamous cell carcinoma in a Chinese population

Variables

Overall survival

Disease-free survival

Hazard ratios

95%CI

P value

Hazard ratios

95%CI

P value

PD-L1

 Negative

1

  

1

  

 Positive

0.882

0.648-1.200

0.423

1.047

0.782-1.401

0.758

Age

 <60 years

1

  

1

  

 ≥60 years

1.623

1.223-2.152

0.001

1.442

1.109-1.875

0.006

Tumor differentiation

 Well

1

  

1

  

 Moderate

1.081

0.736-1.586

0.691

1.192

0.834-1.703

0.334

 Poor

1.369

0.890-2.107

0.153

1.533

1.030-2.280

0.035

 Basaloid

1.109

0.507-2.425

0.796

1.128

0.538-2.367

0.750

PT status

 pT2

1

  

1

  

 pT3-4a

1.119

0.800-1.565

0.512

1.295

0.945-1.776

0.108

PN status

 pN0

1

  

1

  

 pN1

2.054

1.485-2.841

<0.001

2.194

1.617-2.977

<0.001

 pN2

3.316

2.242-4.906

<0.001

3.188

2.201-4.616

<0.001

 pN3

8.016

4.726-13.749

<0.001

7.865

4.682-13.210

<0.001

Vascular invasion

 No

1

  

1

  

 Yes

1.291

0.970-1.718

0.080

1.103

0.831-1.464

0.497

Perineural invasion

 No

1

  

1

  

 Yes

1.328

0.999-1.764

0.051

1.325

1.012-1.736

0.041

Metachronous hematogenous metastasis

 No

1

  

1

  

 Yes

2.073

1.520-2.827

<0.001

3.359

2.499-4.517

<0.001