Table 2 Summaries of 43 cases of mediastinal follicular dendritic cell sarcomas
Case No. | Age/sex | Tumour size (max) | Necrosis | Initial diagnosis | Treatment | Recurrence/Metastasis (mo) | Status | Follow-up (mo) |
|---|---|---|---|---|---|---|---|---|
1 [3] | 62/M | NA | Widespread | FDCS | Surg+ChT | Metastasis (24mo) | STD | 24 |
2 [3] | 46/M | NA | Widespread | FDCS | Surg+RT | No | NED | 12 |
3 [3] | 31/M | NA | No | FDCS | Surg | No | NED | 10 |
4 [4] | 44/F | 3 cm | No | FDCS | ChT | NA | NA | NA |
5 [5] | 43/M | 4 cm | No | Peripheral nerve sheath tumor | Surg | recurrences (36mo) | AWD | 36 |
6 [6] | 42/M | NA | NA | FDCS | Surg | No | NED | NA |
7 [7] | 35/M | 4 cm | Yes | FDCS | RT + ChT | No | STD | 7 |
8 [8] | 76/M | 10 cm | Yes | FDCS | Surg | No | NED | 24 |
9 [9] | 45/M | 15 cm | No | Diffuse large B-cell lymphoma/Tuberculosis | Surg+ChT | multiple recurrences (156mo) | AWD | 204 |
10 [10] | 46/F | 8.4 cm | No | Diffuse large B-cell lymphoma | RT + ChT | Metastasis (12mo) | AWD | 24 |
11 [11] | 43/M | 13 cm | NA | FDCS | Surg | NA | NA | NA |
12 [12] | 45/F | 8.4 cm | NA | Diffuse large B-cell lymphoma | ChT | No | AWD | 22 |
13 [12] | 41/F | 5 cm | NA | FDCS | Surg+RT + ChT | No | NED | 107 |
14 [13] | 60/M | 6 cm | NA | FDCS | Surg+ChT | No | STD | 6 |
15 [14] | 49/F | 9 cm | NA | FDCS | Surg | No | NED | 28 |
16 [15] | 39/M | 8 cm | NA | FDCS | Surg | NA | NA | NA |
17[16] | 23/M | 8 cm | Focal | Malignant nerve sheath tumor | Surg+RT + ChT | Metastasis (45mo) | AWD | 45 |
18 [17] | 72/F | NA | NA | FDCS | Surg | No | NED | 8 |
19 [18] | 47/M | 7.5 cm | NA | FDCS | RT | No | AWD | 14 |
20 [19] | 52/F | NA | Yes | FDCS | Surg | NA | NA | NA |
21 [20] | 42/M | 6 cm | NA | Malignancy | Surg+RT | No | NED | 20 |
22 [21] | 68/M | 4.5 cm | No | FDCS | Surg | No | NED | 24 |
23 [22] | 63/M | 13.4 cm | Widespread | Malignant neoplasm(thymic epithelial origin) | Surg | NA | NA | NA |
24 [23] | 37/M | 11 cm | Yes | necrotic material with no well-defined granulomas | Surg+RT + ChT | No | NED | 6 |
25 [24] | 62/M | 7.5 cm | NA | No atypical cells were obtained | Surg+RT | No | STD | 7 |
26 [25] | 34/M | NA | NA | Low-grade non-Hodgkin lymphoma | Surg+RT + ChT | multiple recurrences (131mo) | AWD | 312 |
27 [26] | 39/M | 6 cm | NA | FDCS | Surg+RT | No | NED | 96 |
28 [27] | 72/F | 4.3 cm | NA | FDCS | RT | Metastasis (12mo) | STD | 12 |
29 [27] | 51/F | 9.1 cm | NA | FDCS | Surg+RT | Metastasis (10mo) | STD | 10 |
30 [27] | 53/F | 10.3 cm | NA | FDCS | Surg | No | NED | 18 |
31 [28] | 29/M | 10 cm | No | NA | Surg+ChT | multiple recurrences (48mo) | AWD | 102 |
32 [28] | 25/M | 13.5 cm | Widespread | NA | Surg+RT + ChT | No | NED | 13 |
33 [28] | 20/F | 11.5 cm | No | NA | Surg | NA | NA | NA |
34 [28] | 61/M | 14 cm | No | NA | Surg+RT + ChT | No | STD | 57 |
35 [28] | 40/F | 4.2 cm | No | NA | Surg | NA | NA | NA |
36 [28] | 23/M | 6.3 cm | Focal | NA | Surg | No | NED | NA |
37 [29] | 16/F | 8 cm | No | FDCS | Surg | No | NED | 24 |
38 [30] | 46/F | 11 cm | NA | Mediastinitis/Hodgkin lymphoma | Surg+RT + ChT | Metastasis (25mo) | STD | 28 |
39 [31] | 27/F | 17 cm | NA | Suspicion of malignancy | ChT | No | STD | 6 |
40 [32] | 71/F | 5.9 cm | NA | NA | Surg+RT | No | NED | 15 |
41 | 52/F | 5 cm | Focal | Suspicion of Hodgkin lymphoma | Surg+ChT | No | NED | 60 |
42 | 46/M | 13 cm | Widespread | Malignant neoplasm | Surg | NA | NA | NA |
43 | 65/M | 9.5 cm | No | FDCS | NA | NA | NA | NA |