Skip to main content

Table 2 Summaries of 43 cases of mediastinal follicular dendritic cell sarcomas

From: Mediastinal follicular dendritic cell sarcoma: a rare, potentially under-recognized, and often misdiagnosed disease

Case No. Age/sex Tumour size (max) Necrosis Initial diagnosis Treatment Recurrence/Metastasis (mo) Status Follow-up (mo)
1 [3] 62/M NA Widespread FDCS Surg+ChT Metastasis (24mo) STD 24
2 [3] 46/M NA Widespread FDCS Surg+RT No NED 12
3 [3] 31/M NA No FDCS Surg No NED 10
4 [4] 44/F 3 cm No FDCS ChT NA NA NA
5 [5] 43/M 4 cm No Peripheral nerve sheath tumor Surg recurrences (36mo) AWD 36
6 [6] 42/M NA NA FDCS Surg No NED NA
7 [7] 35/M 4 cm Yes FDCS RT + ChT No STD 7
8 [8] 76/M 10 cm Yes FDCS Surg No NED 24
9 [9] 45/M 15 cm No Diffuse large B-cell lymphoma/Tuberculosis Surg+ChT multiple recurrences (156mo) AWD 204
10 [10] 46/F 8.4 cm No Diffuse large B-cell lymphoma RT + ChT Metastasis (12mo) AWD 24
11 [11] 43/M 13 cm NA FDCS Surg NA NA NA
12 [12] 45/F 8.4 cm NA Diffuse large B-cell lymphoma ChT No AWD 22
13 [12] 41/F 5 cm NA FDCS Surg+RT + ChT No NED 107
14 [13] 60/M 6 cm NA FDCS Surg+ChT No STD 6
15 [14] 49/F 9 cm NA FDCS Surg No NED 28
16 [15] 39/M 8 cm NA FDCS Surg NA NA NA
17[16] 23/M 8 cm Focal Malignant nerve sheath tumor Surg+RT + ChT Metastasis (45mo) AWD 45
18 [17] 72/F NA NA FDCS Surg No NED 8
19 [18] 47/M 7.5 cm NA FDCS RT No AWD 14
20 [19] 52/F NA Yes FDCS Surg NA NA NA
21 [20] 42/M 6 cm NA Malignancy Surg+RT No NED 20
22 [21] 68/M 4.5 cm No FDCS Surg No NED 24
23 [22] 63/M 13.4 cm Widespread Malignant neoplasm(thymic epithelial origin) Surg NA NA NA
24 [23] 37/M 11 cm Yes necrotic material with no well-defined granulomas Surg+RT + ChT No NED 6
25 [24] 62/M 7.5 cm NA No atypical cells were obtained Surg+RT No STD 7
26 [25] 34/M NA NA Low-grade non-Hodgkin lymphoma Surg+RT + ChT multiple recurrences (131mo) AWD 312
27 [26] 39/M 6 cm NA FDCS Surg+RT No NED 96
28 [27] 72/F 4.3 cm NA FDCS RT Metastasis (12mo) STD 12
29 [27] 51/F 9.1 cm NA FDCS Surg+RT Metastasis (10mo) STD 10
30 [27] 53/F 10.3 cm NA FDCS Surg No NED 18
31 [28] 29/M 10 cm No NA Surg+ChT multiple recurrences (48mo) AWD 102
32 [28] 25/M 13.5 cm Widespread NA Surg+RT + ChT No NED 13
33 [28] 20/F 11.5 cm No NA Surg NA NA NA
34 [28] 61/M 14 cm No NA Surg+RT + ChT No STD 57
35 [28] 40/F 4.2 cm No NA Surg NA NA NA
36 [28] 23/M 6.3 cm Focal NA Surg No NED NA
37 [29] 16/F 8 cm No FDCS Surg No NED 24
38 [30] 46/F 11 cm NA Mediastinitis/Hodgkin lymphoma Surg+RT + ChT Metastasis (25mo) STD 28
39 [31] 27/F 17 cm NA Suspicion of malignancy ChT No STD 6
40 [32] 71/F 5.9 cm NA NA Surg+RT No NED 15
41 52/F 5 cm Focal Suspicion of Hodgkin lymphoma Surg+ChT No NED 60
42 46/M 13 cm Widespread Malignant neoplasm Surg NA NA NA
43 65/M 9.5 cm No FDCS NA NA NA NA
  1. 41–43 Present cases; NA, not available; FDCS, follicular dendritic cell sarcoma; Surg, surgery; RT, radiotherapy; ChT, chemotherapy; NED, no evidence of disease; AWD, alive with disease; STD, succumbed to disease