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Fig. 3 | Diagnostic Pathology

Fig. 3

From: LPS-induced CXCR7 expression promotes gastric Cancer proliferation and migration via the TLR4/MD-2 pathway

Fig. 3

The effect of TLR4 and MD-2 knockdown on LPS-induced CXCR7 expression. a-c: Gastric cancer cells were transfected with TLR4-specific or MD-2-specific shRNAs, and endogenous TLR4 and MD-2 expression levels were analyzed via qRT-PCR (a and b) and western blotting (c); d and e: Gastric cancer cells were transfected with TLR4-specific or MD-2-specific shRNAs and treated with 500 ng/mL LPS. A CCK-8 assay was then used to detect cell proliferation (d), and a transwell assay was used to assess cell migration (e); f and g: As described in D and E, CXCR7 expression was analyzed via RT-PCR (F) and western blotting (g) *, P < 0.05, vs. the Lipo2000 group and sh-NC group. The data are presented as the mean ± SD

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