Analysis of the frequency of oncogenic driver mutations and correlation with clinicopathological characteristics in patients with lung adenocarcinoma from Northeastern Switzerland

Table 2 EGFR mutations in 90 lung cancers

	cDNA change	Amino acid change	Frequency	Percentage
Exon 21	c.2573 T > G	p.L858R	35	38.9
Exon 19	c.2235_2249del/c.2236_2250del^a	p.E746_A750del	33	36.7
Exon 19	c.2240_2257del	p.L747_P753delinsS	6	6.7
Exon 19	c.2254_2277del	p.S752_I759del	3	3.3
Exon 19	c.2239_2253del	p.L747_T751del	2	2.2
Exon 19	c.2239_2248delinsC	p.L747_A750delinsP	2	2.2
Exon 19	c.2238_2252delinsGCA	p.L747_T751delinsQ	1	1.1
Exon 19	c.2239_2256del	p.L747_S752del	1	1.1
Exon 19	c.2237_2255delinsT	p.E746_S752delinsV	1	1.1
Exon 18	c.2126A > C	p.E709A	2	2.2
Exon 18	c.2126A > G	p.E709G	1	1.1
Exon 18	c.2156G > C	p.G719A	1	1.1
Exon 18	c.2155G > T	p.G719C	1	1.1
Exon 20	c.2303G > T	p.S768I	2	2.2
Exon 20	c.2320G > A	p.V774 M	1	1.1
Exon 21	c.2497 T > G	p.L833 V	1	1.1
Exon 21	c.2560A > G	p.T854A	1	1.1

ISSN: 1746-1596