Widely metastatic IDH1-mutant glioblastoma with oligodendroglial features and atypical molecular findings: a case report and review of current challenges in molecular diagnostics

Table 1 Hybrid Capture-Based Targeted Next Generation Sequencing of 644 Cancer Associated Genes (full coding regions)

CDS coding DNA sequence, AA change amino acid change, VAF variant allele frequency, REF reference allele frequency, Avg cov average depth of coverage across all gene-specific exonic targets. Some of the variants with an allele frequency around 50% may be germline; however, the high tumor cellularity (> 90%) of the specimen precludes the distinction of germline from somatic alterations based on %VAF alone
*dnSNP v150 and COSMIC database v82

ISSN: 1746-1596