Table 1 Mutations detected by target-gene sequencing of the retroperitoneal high-grade serous carcinoma
Gene | Amino acid (DNA) substitution | No. wild-type reads | No. mutant reads | MAF |
|---|---|---|---|---|
TP53 | 179H > R (536A > G) | 3 | 50 | 0.94 |
BRCA2 | 2129E > X (6385G > T) | 17 | 89 | 0.84 |
MLL4 | 2009A > V (6026C > T) | 21 | 39 | 0.65 |
SIGLEC9 | Y117H (349T > C) | 33 | 33 | 0.50 |
MUC6 | 1758H > L (5273A > T) | 179 | 15 | 0.08 |