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Table 2 Distribution data for Bcl-2, Bax, Beclin, LC3B, p21 and p16 used for immunohistochemistry according to established scores and p value for difference between solid and non-solid ACCs

From: Role of apoptotic, autophagic and senescence pathways in minor salivary gland adenoid cystic carcinoma

Score

Bcl-2

Bax

Beclin

LC3B

p21

p16

CD34 (%)

CD105 (%)

S

NS

S

NS

S

NS

S

NS

S

NS

S

NS

Mean (SD)

Mean (SD)

n (%)

n (%)

n (%)

n (%)

n (%)

n (%)

n (%)

n (%)

n (%)

n (%)

n (%)

n (%)

0

0 (0,0)

2 (11.8)

7 (87.5)

17 (100)

0 (0,0)

0 (0,0)

3 (37.5)

8 (47.1)

0 (0,0)

4 (23.5)

8 (100)

16 (100)

  

1

3 (37.5)

1 (5.9)

1 (12.5)

0 (0,0)

3 (37.5)

1 (5.9)

1 (12.5)

3 (17.6)

1 (14.3)

2 (11.8)

0 (0,0)

0 (0,0)

3.8 (0.4)

0.39 (0.2)

2

5 (62.5)

14 (82.4)

0 (0,0)

0 (0,0)

5 (62.5)

16 (94.1)

4 (50)

6 (35.3)

6 (85.7)

11 (64.7)

0 (0,0)

0 (0,0)

  

p

• 0.53

• 0.32

• 0.08

• 0.64

• 0.26

■ 0.0001

  1. Legend: 0 = absent; 1 = weak; 2 = strong staining
  2. • = Mann-Whitney test for S (solid) and NS (non solid) minor salivar ACC
  3. ■ = Student t test
  4. Pearson correlation Bcl-2 and Beclin = p = 0.014; r = 0.483