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Table 2 Pre- and post-radiotherapy findings of studied patients compared with healthy levels

From: Changes in plasma EBV-DNA and immune status in patients with nasopharyngeal carcinoma after treatment with intensity-modulated radiotherapy

Parameters

HD

Pre

Post

P 1

P 2

OR

95%CI

N

(106/ml)

3.30

(2.00–5.90)

3.90

(1.70–13.20)

3.31

(0.95–23.49)

0.06

0.03

0.46

(0.18, 1.15)

L

(106/ml)

2.05

(1.00–3.50)

1.30

(0.20–6.00)

0.43

(0.12–2.32)

0.00

0.00

29.71

(3.68, 239.94)

NLR

(106/ml)

1.60

(0.90–3.30)

2.47

(1.29–29.50)

8.24

(1.34–68.21)

0.00

0.00

0.19

(0.06, 0.55)

EBV DNA

(copies/ml)

56.11

(0.00–3213.50)

1132.56

(0.00–19065.22)

35.67

(0.00–5678.50)

0.00

0.00

0.02

(0.00, 0.20)

CD4+

(106/ml)

0.70

(0.18–1.20)

0.37

(0.05–1.09)

0.07

(0.00–073)

0.00

0.00

9.50

(2.81, 32.10)

Treg

(106/ml)

0.08

(0.04–0.23)

0.09

(0.01–0.26)

0.02

(0.00–0.16)

0.68

0.00

0.86

(0.35, 2.10)

CD8+

(106/ml)

8.49

(3.02–14.85)

3.42

(0.00–7.16)

0.22

(0.00–0.75)

0.00

0.00

20.06

(4.21, 95.56)

CD8+PD1+

(106/ml)

0.19

(0.05–0.45)

0.13

(0.03–0.58)

0.05

(0.01–0.19)

0.02

0.00

3.17

(1.21, 8.30)

  1. N absolute neutrophil count, L absolute lymphocyte count, NLR neutrophil lymphocyte ratio, Treg CD4+CD25+CD127low, P1 Healthy Donor& Pre-radiotherapy, P2 Pre-radiotherapy &Post-radiotherapy, OR the odds ratio, 95%CI 95% confidence intervals