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Table 4 Values of sensitivity, specificity, and predictive values of the predicted probability at the optimal cutoff value

From: A nomogram for predicting the HER2 status in female patients with breast cancer in China: a nationwide, multicenter, 10-year epidemiological study

 

The Optimal Cutoff

Sensitivity

Specificity

PPV

NPV

Training set

0.212

80.0%

43.1%

32.4%

86.4%

Validation set

0.204

81.1%

49.8%

31.5%

90.2%

  1. NPV negative predictive value, PPV positive predictive value
  2. *The optimal cutoff value is determined according to the Youden’s method