Table 2 Association between SNW1 staining and prostate cancer phenotype
SNW1 (%) | ||||||
|---|---|---|---|---|---|---|
Parameter | N | Negative | Weak | Moderate | Strong | P |
All cancers | 10,310 | 16.9 | 31.5 | 37.7 | 14.0 | |
Tumor stage | < 0.0001 | |||||
pT2 | 6668 | 18.7 | 33.2 | 36.3 | 11.8 | |
pT3a | 2289 | 15.0 | 27.0 | 40.3 | 17.6 | |
pT3b-pT4 | 1313 | 10.2 | 30.2 | 40.1 | 19.5 | |
Gleason grade | < 0.0001 | |||||
≤ 3 + 3 | 2302 | 25.0 | 34.2 | 31.9 | 8.9 | |
3 + 4 | 5275 | 16.1 | 31.2 | 38.0 | 14.7 | |
3 + 4 Tertiary 5 | 382 | 13.6 | 31.2 | 43.5 | 11.8 | |
4 + 3 | 916 | 12.2 | 27.9 | 41.2 | 18.7 | |
4 + 3 Tertiary 5 | 564 | 9.8 | 25.2 | 41.8 | 23.2 | |
≥ 4 + 4 | 420 | 7.9 | 28.1 | 46.2 | 17.9 | |
Lymph node metastasis | < 0.0001 | |||||
N0 | 5818 | 16.0 | 30.4 | 38.5 | 15.1 | |
N+ | 591 | 8.3 | 27.6 | 45.2 | 19.0 | |
Preoperative PSA level (ng/ml) | 0.0011 | |||||
< 4 | 1278 | 13.2 | 30.0 | 41.6 | 15.2 | |
4–10 | 6160 | 16.8 | 31.4 | 37.4 | 14.4 | |
10–20 | 2047 | 18.1 | 32.6 | 36.3 | 13.0 | |
> 20 | 713 | 19.1 | 31.0 | 37.4 | 12.5 | |
Surgical margin | 0.0034 | |||||
Negative | 8178 | 17.4 | 31.7 | 37.5 | 13.5 | |
Positive | 1947 | 14.8 | 30.8 | 38.4 | 16.0 | |