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Table 3 Cox proportional hazards for PSA recurrence-free survival after prostatectomy of established preoperative prognostic parameter and SNW1 expression

From: SNW1 is a prognostic biomarker in prostate cancer

Variable

Univariable analysis

Multivariable analysis

Gleason grade biopsy

  ≥ 4 + 4 vs. ≤3 + 3

6.01 (5.41–6.66) ***

4.05 (3.58–4.58) ***

Preoperative PSA-level (ng/μl)

  > 20 vs. < 4

5.12 (4.46–5.89) ***

3.61 (3.00–4.35) ***

cT-stage

 T2b vs. T1c

2.16 (1.73–2.66) ***

1.84 (1.62–2.08) ***

SNW1 expression

 Strong vs. negative

1.95 (1.69–1.26) ***

1.63 (1.40–1.89) ***

 ERG negative subset

2.38 (1.90–2.97) ***

1.88 (1.49–2.35) ***

 ERG positive subset

1.81 (1.30–2.60) **

1.48 (1.06–2.14) *

  1. The multivariable model included all the four-univariate factors. Confidence interval (95%) in brackets; asterisk indicate significance level: * p ≤ 0.05, ** p ≤ 0.001, *** p ≤ 0.0001; ERG ETS-related gene