Fig. 2From: Positive/retained SDHB immunostaining in renal cell carcinomas associated to germline SDHB-deficiency: case reportSecond renal cancer. a Similar morphology to the previous tumor, composed oncocytic cells with different grades of eosinophilic cytoplasm (HE × 200). b Nuclei with evenly distributed chromatin (HE × 400). c Tumor cells stain positive for SDHB immunohistochemistry (SDHB × 200). d SDHB staining showing a cytoplasmic mitochondrial pattern. Just as in the previous tumor, entrapped tubules at the periphery are more intense for SDHB immunohistochemistry than tumor cells, arrowhead (SDHB × 400)Back to article page