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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Tumor-to-tumor metastasis: a rare case of breast carcinoma metastasizing to a pheochromocytoma, and a literature review

Fig. 3

The cut surface of the tumor is divided into two parts: whitish and pinkish-grey (a). Histological staining with hematoxylin and eosin shows that the cells of both parts are similar (b). The proliferative index (Ki67) of metastatic breast cancer is significantly higher than that of pheochromocytoma (c). Immunohistochemistry shows that pheochromocytoma cells are strongly positive for CgA, SYN and CD56 (d, e and f), and metastatic breast carcinoma cells are strongly positive for CK, HER-2 and membrane positive for E-cadherin (g, h and i)

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