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Table 1 Clinical features for patients with or without renal endpoints

From: Updated Oxford classification and the international study of kidney disease in children classification: application in predicting outcome of Henoch-Schönlein purpura nephritis

Clinical features

Renal endpoints reached

P value

Yes

No

Number of patients

30

245

 

Mean age (years)

42 ± 22

33 ± 16

0.052

Gender (Male/Female)

21/9

122/123

0.036

Extrarenal manifestation

 Skin (n, %)

30 (100%)

245 (100%)

 

 Gastrointestinal tract (n, %)

4 (13.3%)

62 (24.3%)

0.147

 Joints (n, %)

1 (3.3%)

45 (18.4%)

0.068

MAP (mmHg)

100 ± 9

94 ± 11

0.012

Scr (μmol/L)

103.0 (74.8217.8)

63.0 (53.0,78.0)

<0.001

eGFR (ml/min/1.73m2)

67.4 (30.1, 115.4)

121.2 (92.6, 140.1)

<0.001

Proteinuria(g/24 h)

2.7 (1.0, 5.0)

1.12 (0.6, 2.7)

<0.001

Immunosuppressant therapy (n, %)

24 (80.0%)

176 (71.8%)

0.343

 Steroids only(n)

6

93

0.019

 Steroids + IVC/MMF(n)

18

83

ACEI/ARB

12 (40.0%)

83 (33.9%)

0.51

  1. The data were expressed as mean ± s.d. or as numbers(percentage)
  2. Results of Scr, eGFR, proteinuria were expressed as median (interquartile range)
  3. MAP mean arterial pressure, Scr serum creatinine, eGFR estimated glomerular filtration rate, IVC intravenous cyclophosphamide, MMF mycophenolate mofetil, ACEI angiotensin converting enzyme inhibitor, ARB angiotensin II receptor blocker