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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Interobserver variability and accuracy of p16/Ki-67 dual immunocytochemical staining on conventional cervical smears

Fig. 2

A few cases where p16/Ki-67 DS was difficult to interpret. a Weak p16 staining of the cytoplasm in a case where even the expert was not sure whether the test could be called positive. b Arrow points to a nucleus where it is difficult to differentiate intense p16 from Ki-67 staining. c A group of cells designated as suspicious for p16/Ki-67 DS by the cytotechnologists/cytopathologists and by the expert (reference2). d A group of cells where it is difficult to decide whether the p16/Ki-67 DS can be called positive

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